Effect of treatment with neem [azadirachta indica] compared with baycox drug on the caecum of chicken experimentally infected with eimeria tenella

The study evaluated the therapeutic efficacy of Neem herb in chicken experimentally infected with E. tenella compared to Baycox as a reference anticoccidial drug. 120 broiler chicks were enrolled, randomly divided to 4 groups, [A, B, C and D] non-infected non-treated [naive control], [B] infected with 10[4] E. tenella oocysts [infected control], [C] infected and treated with Baycox [7 mg/kg b.w. for 2 days] and [D] infected and treated with Neem leaves water extract [100 mg/kg b.w. for 9 days]. Evaluation was by clinical signs, performance data [gain weigh, food consumption oocyst shed/gram feaces [OPG]], in addition to histopathological changes in all chickens. The results revealed that chicks of GA had the best performance data compared to GB, GC and GD. In GC and GD there were a remarkable improvement in the data performance, clinical signs, gross and microscopically cecal lesions compared to GB. The efficacy of Baycox [GC] was shown to be superior to that of Neem [GD] compared to GB but an additive histopathological toxic effect besides those produced by E. tenella infection could be recorded. In contrast, Neem appeared to have a remarkable improvement on cecal integrity

Effect of aflatoxin on the coccidial infection in broilers

Two hundred of one day old chickens were divided into four equal groups and kept for the end of experiment. The first group was kept as control negative, the second group received 1 ppm of dietary aflatoxin from day zero of chick life till the end of present study, while the third group was given 4x10[4] sporulated oocysts of Eimeria sp., the group four were obtained coccidial oocysts and aflatoxin in their rations. The combination of aflatoxin and coccidia, produced higher mortality rate, higher faecal scores and increased oocysts output than those chicks received aflatoxin or coccidia only. Body weighs and efficiency of feed utilization were decreased in all treated groups. The maximal losses of body weight and efficiency of feed utilization were noticed in chicks infected with Eimeria sp. and at received aflatoxin in their ration. The levels of total serum proteins, gamma globulins, calcium and phosphorus were decreased in chicks infected with coccidia and received dietary aflatoxin. Total bilirubin and SGOT activity were higher in chicks infected with Eimeria sp, and obtained aflatoxin

Efficacy of garlic extract on hepatic coccidiosis in infected rabbits [oryctolagus cuniculus]: histological and biochemical studies

The rabbits were divided into three groups, of 12 rabbits each. G1 was the [non-infected non-treated] as control, G2 was the [infected-non treated], and G3 was the [infected and treated] rabbits. Each rabbit in the infected groups were given [10[3]] sporuleted oocysts of Eimeria stiedae per rabbit after forty five days exactly. Faecal sample of rabbits from each group were examined each day post infection till oocysts appeared in faeces. The treatment was given by using suitable dosage of garlic according to body weight. After 15, 21, 28, and 35 days post-treatment faecal oocysts were output. Biochemical parameters as serum liver function [ALT, AST, GGT and ALP] that denoted the he-patic cells injury. The results showed a significant differences in the mean values of oocysts shedding and their mean number in bile ducts between Gs 2 and 3 from the 15[th] day post infection [PI] [mean +/- SD:40.33 +/- 16.72 and 25.17 +/- .56 respectively] till the experimental end on the 35[th] day [55.75 +/- 19.79 and 0.94 +/- 1.43 respectively]. The histopathological alterations were in liver of G2 at the experimental end. Coccidiosis in G2 induced histopathological alterations in liver tissue, marked cytoplasmic vacuolations in hepatocytes with clear signs of karyolysis, and dilatation of sinusoids with increase in Kupffer cells. Leukocytic infiltration around congested blood vessels was noticed. Efficacy of garlic on E. stiedae in infected Gs was resident. The liver of G3 regained almost normal appearance compared to control